By Free Republic | Created at 2024-11-13 22:58:28 | Updated at 2024-11-23 08:24:56
1 week ago
Psilocybin shows promise as new treatment for OCD and Tourette's syndrome, finds study
Medical Xpress / Hebrew University of Jerusalem / Molecular Psychiatry ^ | Oct. 29, 2024 | Michal Brownstien et al
Posted on 11/13/2024 2:53:19 PM PST by ConservativeMind
A study led by Prof. Bernard Lerer shows promising results for using psilocybin, a psychedelic compound, as a potential treatment for obsessive-compulsive disorder (OCD) and Tourette's syndrome.
The research provides significant insights into the benefits of psilocybin for managing symptoms similar to those experienced by people with OCD and Tourette's syndrome.
The study included 50 genetically modified mice that displayed excessive grooming and anxiety, similar to human OCD behaviors and head-body twitches similar to tics suffered by patients with Tourette's syndrome.
These mice were randomly given either a single injection of psilocybin, a psychedelic mushroom extract, or a placebo. Raters, unaware of which treatment each mouse received, evaluated the effects at several points over a three-week period.
Mice treated with psilocybin showed a 14.60% decrease in excessive grooming, while those receiving the mushroom extract saw a 19.20% reduction, compared to a significant increase of 118.71 in grooming in the placebo group. The study also observed reductions in other symptoms like tic-like movements and anxiety, with the mushroom extract showing greater benefit in its effect on anxiety. Additionally, the positive effects from a single treatment lasted up to seven weeks in some mice.-0
"Understanding that over 40% of OCD patients don't find relief with current treatments, our findings are crucial as they suggest a new way to help these individuals," Prof. Lerer noted.
"We look forward to advancing to human trials and further exploring how these treatments can provide long-term benefits. The effects observed on tic-like head and body twitches raise the previously unreported possibility that psilocybin may be effective in patients with Tourette's syndrome."
This research highlights the potential of psilocybin and similar substances in treating psychiatric conditions and supports ongoing efforts to discover new, effective mental health therapies.
(Excerpt) Read more at medicalxpress.com ...
TOPICS: Health/Medicine
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This is available today with the drug Indocybin, but may need to be used off label.
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2 posted on 11/13/2024 2:53:47 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
To: ConservativeMind
Psilocybin shows promise as new treatment for Tourette's
DAMN I love those mushrooms!
3 posted on 11/13/2024 2:55:07 PM PST by Jeff Chandler (THE ISSUE IS NEVER THE ISSUE. THE REVOLUTION IS THE ISSUE.)
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