Breakthrough as woman's type 1 diabetes is CURED in world-first using stem cells

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Posted on 09/27/2024 7:30:56 PM PDT by Red Badger

A woman in China's type 1 diabetes has been reversed thanks to a novel treatment that retools cells extracted from the patient's own body.

The breakthrough cure converted these cells into personalized stem cells that were then used to grow clusters of fresh 'islets', hormone-producing cells in the pancreas and liver that help to regulate sugars in the body.

'I can eat sugar now,' said the 25-year-old, who lives in the city of Tianjing, where researchers say her body has successfully produced its own insulin for over a year.

The treatment, which outside experts have called stunning and 'wonderful,' builds on a related milestone in Shanghai in April.

That April case was different in that it involved transplanting stem cells into the liver, whereas the new method involved transplanting the newly made islets into the patient's upper abdomen near her pancreas.

Prior islet transplants into the liver have been harder to observe via noninvasive methods like MRI, experts said, making it harder to remove these cell-clusters in a worst case where a patient's immune system rejects and attacks the transplant.

This new method, inserting the islets just under the abdomen, allowed researchers to monitor the progress of these islets via MRI with comparative ease.

'They've completely reversed diabetes in the patient, who was requiring substantial amounts of insulin beforehand,' transplant surgeon Dr James Shapiro, who was not involved in the new study, told the journal Nature, approvingly.

[SNIP]

Therefore it remains unclear if other patients' bodies might reject a transplant of similar islets derived from their own, personal extracted cells.

The June 2023 operation, as the team published in the journal Cell on Wednesday, took less than half an hour.

(Excerpt) Read more at dailymail.co.uk ...

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1 posted on 09/27/2024 7:30:56 PM PDT by Red Badger

To: Red Badger

2 posted on 09/27/2024 7:34:13 PM PDT by Harmless Teddy Bear ( Not my circus. Not my monkeys. But I can pick out the clowns at 100 yards.)

To: Red Badger

3 posted on 09/27/2024 8:01:01 PM PDT by july4thfreedomfoundation (I "earned" the same number of delegates during the primaries in 2020 and 2024 as Harris.)

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