Dietary compound increases longevity and protects against Alzheimer's disease in experimental models (Phytoene)

By Free Republic | Created at 2024-09-29 05:31:23 | Updated at 2024-09-30 09:36:21 1 day ago
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Dietary compound increases longevity and protects against Alzheimer's disease in experimental models (Phytoene)
Medical Xpress / University of Seville / Antioxidants ^ | Sept. 26, 2024 | Ángeles Morón-Ortiz et al

Posted on 09/28/2024 9:03:36 PM PDT by ConservativeMind

Researchers have shown that the carotenoid phytoene increases the lifespan of the nematode Caenorhabditis elegans and can slow the onset of paralysis associated with the formation of amyloid plaques in a model of Alzheimer's disease.

Specifically, increases in longevity of between 10% and 18.6% and decreases in the proteotoxic effect of plaques of between 30% and 40% were observed.

The studies tested pure phytoene and extracts rich in this carotenoid obtained from microalgae.

According to Dr. Paula Mapelli Brahm, "These are very exciting preliminary results, so we are looking for funding to continue this line of research and to find out by what mechanisms these effects are produced."

Caenorhabditis elegans is a widely used animal model in biomedicine. In fact, it has been instrumental in important discoveries that have been recognized with the Nobel Prize, such as programmed cell death, RNA interference and applications of the GFP protein.

Professor Antonio Jesús Meléndez Martínez's team has spent 15 years studying phytoene, which is found in foods such as tomatoes, carrots, apricots, red peppers, oranges, mandarins and passion fruit, among others. It is a compound that is efficiently absorbed and found in many tissues, including the skin, where studies indicate that it can protect against ultraviolet radiation.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: carotenoid; phytoene

Phytoene is in Yaeyama Chlorella Powder (available in health good stores and Amazon) and in smaller amounts in foods that have lycopene, like tomatoes, carrots, and oranges.


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2 posted on 09/28/2024 9:04:17 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)


To: All

Researchers have shown that the carotenoid phytoene increases the lifespan of the nematode Caenorhabditis elegans

When I read the news of this to my nematode Caenorhabditis elegans, they were overjoyed.

3 posted on 09/28/2024 9:15:23 PM PDT by BipolarBob (You may call me blind, deaf and dumb but I'm sill a Pinball Wizard.)


To: ConservativeMind

Looks like the tablets are inexpensive: $0.04 ea in the 600 tablet container.


4 posted on 09/28/2024 9:28:14 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)


To: BipolarBob

If it’s only one nematode, you should have said “it,” not “they.”


5 posted on 09/28/2024 10:00:36 PM PDT by reasonisfaith (What are the personal implications if the Resurrection of Christ is a true event in history?)

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