Claudia Sheinbaum, who took office last month, said during a press conference on Wednesday that she was “convinced” relations with Washington would remain positive.
“We are a free, independent, sovereign country and there will be good relations with the United States,” she added.
The president also tried to calm the markets after the Republican’s victory sent the Mexican peso to its lowest value against the dollar in two years, reflecting anxiety about possible trade tensions.
The Mexican peso opened down more than 3 per cent on Wednesday, trading at US$0.048 per dollar.
The performance echoed other currencies from developing countries that registered devaluation against the US dollar.