Mild initial clinical course seen for COVID-19 vaccine-linked myocarditis

By Free Republic | Created at 2024-09-22 16:53:36 | Updated at 2024-09-30 09:36:45 1 week ago
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Mild initial clinical course seen for COVID-19 vaccine-linked myocarditis
Medical Xpress / HealthDay / NY Med College-Maria Fareri Children's Hospital / eClinicalMedicine ^ | Sept. 19, 2024 | Elana Gotkine / Supriya S. Jain et al

Posted on 09/22/2024 9:52:02 AM PDT by ConservativeMind

COVID-19 vaccine-associated myocarditis (C-VAM) has a mild initial clinical course, but myocardial injury is common, according to a study.

Supriya S. Jain, M.D. and colleagues examined the clinical characteristics, myocardial injury, and longitudinal outcomes of C-VAM.

A total of 333 patients aged 30 years or younger with C-VAM were compared to 100 patients with multisystem inflammatory syndrome in children (MIS-C). The presence of myocardial injury as evidenced by late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging was the primary outcome.

Patients with C-VAM were mainly White (67%), adolescent (age, 15.7 ±2.8 years) males (91%). The researchers found that compared with MIS-C, the initial clinical course of C-VAM was significantly more likely to be mild (80 versus 23%) and cardiac dysfunction was less common (17 versus 68%). LGE on CMR was significantly more prevalent in C-VAM than MIS-C (82 versus 16%).

The probability of LGE was significantly higher in male and older patients and when C-VAM occurred after the first or second versus the third mRNA vaccine dose. At a median follow-up of 178 days, midterm clinical outcomes of C-VAM were reassuring. In 60% of patients, LGE persisted at follow-up.

"While midterm clinical sequelae are rare and LGE severity decreases over time, the persistence of LGE at follow-up in most patients warrants continued clinical surveillance, additional research, and longer-term studies in this subset of patients," the authors write.

(Excerpt) Read more at medicalxpress.com ...


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COVID-19 vaccine-induced “myocardial injury is common,” especially in “adolescent males” averaging “15.7 years.”

Myocardial injury as evidenced by late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging” “was significantly more prevalent in C-VAM (COVID-19 vaccination-induced myocarditis)” than even in those poor patients dealing with “MIS-C (Multisystem Inflammatory Syndrome) (82% versus 16%).”

Folks, I would never encourage giving a COVID-19 vaccine shot to younger people. The doctors who visit on Free Republic have all stated the same, from what I have ever seen, however, we do have some other FReepers who have felt otherwise.


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2 posted on 09/22/2024 9:52:34 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)

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