By Free Republic | Created at 2024-11-27 04:15:59 | Updated at 2024-11-27 06:36:38
2 hours ago
Probiotic may counteract fire-retardant chemical damage (L. Reuteri)
Medical Xpress / University of California - Riverside / Archives of Toxicology ^ | Nov. 22, 2024 | Iqbal Pittalwala / Maximillian E. Denys et al
Posted on 11/26/2024 8:06:05 PM PST by ConservativeMind
Polybrominated diphenyl ethers, or PBDEs, are fire-retardant chemicals that are found everywhere—upholstery, carpets, curtains, electronics, and even infant products. Known to disrupt hormones and persist in the environment, these pollutants have been detected in human tissues and even breast milk.
A mouse study reports that probiotic supplementation can reduce the negative impacts of PBDEs on neurodevelopment, behavior, and metabolism.
"Exposure to PBDEs during the perinatal period produces autistic-like behavior and metabolism syndrome in mice," said Margarita C. Curras-Collazo. "These compounds also disrupt the gut microbiome, which has been linked to brain and metabolic health. Our study shows supplementing the maternal diet with the probiotic Limosilactobacillus reuteri can help prevent these negative effects."
The researchers exposed mouse mothers to a PBDE mixture or a control (corn oil) during pregnancy and breast-feeding. This was done over a 10-week period. Some of the mice were supplemented with LR.
They found male offspring exposed to PBDEs had a delay in body weight gain. Further, their incisor eruption was abnormally timed.
"To our surprise, we found LR treatment prevented delays in male weight gain and helped normalize the timing of tooth eruption in both sexes," said Elena Kozlova.
This was a particularly significant result.
"Low birth weight is an established predictor of adult health outcomes."
The research team also found that the exposed female offspring showed exaggerated digging and hyperactivity in adulthood; LR mitigated these effects. Moreover, glucose metabolism and insulin levels improved in adult female offspring exposed to the PBDE mixture that were also given LR directly.
"Maternal probiotic therapy with LR corrected most of the behavioral and metabolic abnormalities caused by PBDE exposure," Kozlova said. "We gave offspring the probiotics through the mother, which is a very effective way to mitigate the effects of PBDEs with low risk to the developing offspring."
(Excerpt) Read more at medicalxpress.com ...
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L. reuteri is available in Lifeway Kefir and supplement form.
I first took it in capsule form (Nature’s Way) about 20 years ago.
It appears to mitigate some toxic concerns from fire retardants.
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2 posted on 11/26/2024 8:06:41 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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