Researchers discover why taking a mushroom supplement slows or prevents prostate cancer from getting worse
Medical Xpress / City of Hope National Medical Center / Clinical and Translational Medicine ^ | Nov. 12, 2024 | Xiaoqiang Wang et al
Posted on 11/25/2024 8:25:44 PM PST by ConservativeMind
Researchers now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined a phase 2 clinical trial studying "food as medicine."
Looking at preclinical and preliminary human data, the scientists found that taking white button mushroom pills reduces a class of immune cells called myeloid-derived suppressor cells (MDSCs), which has been linked to cancer development and spread.
"City of Hope researchers are investigating foods like white button mushroom, grape seed extract, pomegranate, blueberries and ripe purple berries called Jamun for their potential medicinal properties. We're finding that plant-derived substances may one day be used to support traditional cancer treatment and prevention practices," said Shiuan Chen, Ph.D.
"This study suggests that 'food as medicine' treatments could eventually become normal, evidence-based cancer care that is recommended for everyone touched by cancer."
In mouse models, researchers found that administration of white button mushroom extract significantly delayed the growth of tumors and extended the survival of mice. It also improved T cell immune response through the reduction of MDSC levels in animal models, meaning it improved the immune system's ability to kill cancer.
The researchers profiled blood draws from some of the men participating in City of Hope's phase 2 clinical trial. The men were under active surveillance as they took white button mushroom supplements. Focusing on eight participants' samples before and after three months of white button mushroom treatment, the scientists found that there were less tumor-creating MDSCs and more anti-tumor T and natural killer cells, suggesting white button mushroom rebuilds anti-cancer immune defense and slows cancer growth.
(Excerpt) Read more at medicalxpress.com ...
TOPICS: Health/Medicine
KEYWORDS: blueberries; buttonmushrooms; cancer; foodasmedicine; grapeseed; grapeseedextract; jamun; mushroom; mushrooms; pomegranate; pomegranates; prostatecancer; whitebuttonmushrooms
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Everyone can find white button mushrooms to eat.
It might even help with your prostate cancer.
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2 posted on 11/25/2024 8:26:16 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
To: ConservativeMind
3 posted on 11/25/2024 8:31:54 PM PST by linMcHlp
To: ConservativeMind
Most likely not limited to just prostate cancer.
4 posted on 11/25/2024 8:31:55 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
To: ConservativeMind
Taste good cooked in butter.
5 posted on 11/25/2024 9:00:20 PM PST by IDFbunny (Crimea was never Ukraine.)
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