Scientists discover proteins in meat, milk and other foods suppress gut tumors

By Free Republic | Created at 2024-09-22 03:26:57 | Updated at 2024-09-30 07:26:43 1 week ago
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Scientists discover proteins in meat, milk and other foods suppress gut tumors
Medical Xpress / RIKEN / Frontiers in Immunology ^ | Sept. 18, 2024 | Takaharu Sasaki, Ohno, et al

Posted on 09/21/2024 8:13:03 PM PDT by ConservativeMind

Researchers have discovered that food antigens like milk proteins help keep tumors from growing in the small intestines.

Food antigens are the source of allergic reactions to foods.

Ohno previously reported that food antigens activate immune cells in the small intestines, but not the large intestines.

In the new study, researchers tested whether food antigens suppress tumors in the small intestines.

The team began with a special kind of mouse. The mice develop tumors throughout the small and large intestines.

The first experiment was fairly simple. They fed these mice normal food or antigen-free food and found that the ones that got normal food had fewer tumors in the small intestines.

Next, they added a common representative antigen called albumin—which can be found in meat—to the antigen-free diet.

When the mice were given this diet, tumors in the small intestine were suppressed just as they had been with normal food. This means that tumor suppression was directly related to the presence of antigen.

The diets also affected T cells in the small intestines. Mice that got the plain antigen-free diet had many fewer T cells than those that got the normal food or the antigen-free food with milk protein.

These findings have clinical implications. Similar to antigen-free diets, clinical elemental diets include simple amino acids, but not proteins. This can help people with gastrointestinal conditions.

According to Ohno, "small intestinal tumors are much rarer than those in the colon, but the risk is higher in cases of familial adenomatous polyposis, and therefore the clinical use of elemental diets to treat inflammatory bowel disease or other gastrointestinal conditions in these patients should be considered very carefully."

Elemental diets are sometimes adopted as a healthy way to lose weight and inflammation. The new findings suggest that this could be risky.

(Excerpt) Read more at medicalxpress.com ...


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We appear to need food antigens, which help keep T cells in the small intestine, which then curb cancer.


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2 posted on 09/21/2024 8:13:45 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)


To: ConservativeMind

3 posted on 09/21/2024 8:24:27 PM PDT by TribalPrincess2U (Bye done!)

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