Cancer experts issue call for 250,000 volunteers in bid to discover why UK has one of the fastest-rising rates

By GB News (World News) | Created at 2026-10-05 08:00:57 | Updated at 2026-10-05 08:41:30 47 minutes ago

A major new research initiative is being launched to tackle the alarming surge in bowel cancer amongst younger adults across Britain. The Prospect-UK trial will recruit a quarter of a million participants nationwide.

Researchers from King's College London have joined forces with the health science firm Zoe to establish what factors are driving the increase in cases affecting those below the age of 50. Britain ranks amongst the nations experiencing the most rapid acceleration in early-onset bowel cancer globally.


The study will see participants filling in digital questionnaires covering their eating habits, daily routines, environmental exposures and overall wellbeing. A subset of those taking part will be required to maintain comprehensive food journals and supply biological specimens, including blood and stool, for analysis.

The condition, which historically affected primarily older individuals, has seen rates climb substantially worldwide since 1990.

Data from Cancer Research UK reveals approximately 48,200 individuals receive bowel cancer diagnoses annually across the UK. Of this total, roughly 2,900 cases occur in the 25 to 49 age bracket.

The figures demonstrate a marked escalation in incidence. Overall cancer rates amongst the nation's 25- to 49-year-old population climbed by 24 per cent between the early 1990s and 2019, according to the charity.

Excess weight has been identified as one potential contributing element to the rise. However, the precise causes behind the worrying upward trajectory remain unclear.

The research team emphasised whilst early-onset bowel cancer cases are increasing, the disease remains comparatively unusual in individuals under 50 years old. This relative rarity necessitates recruiting substantial numbers of participants to generate meaningful findings.

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Cancer experts have issued a call for 250,000 volunteers

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Professor Sarah Berry, who serves as chief investigator for the trial and holds the position of professor of nutritional sciences at KCL, stressed the urgent requirement for comprehensive information gathering.

"We urgently need large-scale, long-term data to uncover the true causes of early-onset bowel cancer," she said.

Professor Berry highlighted the profound shifts that have occurred within a relatively brief timeframe. "Over just a few generations our lifestyles, diets and environments have changed dramatically," she said.

The knowledge gaps remain significant regarding which factors pose the greatest danger. "But we don't know which of these changes are increasing people's risk of bowel cancer or which ones could help reduce it," she added.

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King's College London has joined forces with the health science firm Zoe

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Participants will be requested to permit researchers to match their submitted information with electronic medical records, enabling scientists to establish connections between specific behaviours and cancer development.

Dr Rosiered-Brownson Smith, a study research associate at KCL, pointed to the growing intricacy of Britain's nutritional landscape as a key area of investigation.

"Our food environment has become increasingly complex, and this means we need to look at diet in much greater detail," she said.

The study will examine the fact highly processed items now account for approximately 60 per cent of average caloric consumption amongst UK adults.

"In the UK, around 60 per cent of our calorie intake comes from highly processed foods, but these foods are not all the same," Dr Smith said. "They can differ substantially in their ingredients, processing methods and nutritional composition, even within the same food category."

The trial represents the first occasion on which investigators will gather specific brand-level details about consumed products. "Combining detailed dietary information with long-term health data, we hope Prospect-UK will help us better understand the complex relationship between what we eat and our risk of disease," she said.

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